The best time to fish at Cayo Romano would be from early April to late June. This is both based upon local weather together with the massive influx of migratory Tarpon that can easily weigh up to 45kg (100lbs). The entire months of July and August offer equally good fishing, but the temperatures can make for a hot angling expedition. If however you are accustomed to the heat then it’s perfectly fine and the fishing in Cayo Romano is great during these key summer months. The months of September to December turn out to be excellent Bonefish month and for reduced quantities of large and medium Tarpon.
From the early part of the season from say January to March there’s still good fishing to be had, primarily Permit and Bonefish as well as varying weights of Tarpon of up to 13kg (30lbs). Cayo Romano is well protected by a string of cays that shelter the majority of the fishing spots from the elements however in these months from Jan-March winds can sometimes be problematic but for many increase the complexity, making the angling more rewarding.